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Get PDF (409K) - Wiley Online Library
The Design of Drugs to Macromolecular Targets. Edited by C R Beddell. pp 287. John Wiley and Sons,. Chichester. 1992. £60. ISBN 0-471-92080-0. This book ...
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Docking Screens for Novel Ligands Conferring - ACS Publications
Feb 25, 2016 ... John J. Irwin* and Brian K. Shoichet*. Department ... target quality, and methods that have supported these advances, and the open access resources ... promoted for structure-based or “rational” drug design.1,2 The techniques ...... (1) Beddell, C. R.; Goodford, P. J.; Norrington, F. E.; Wilkinson, S.;. Wootton ...
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medicinal - ACS Publications - American Chemical Society
Molecular Modeling in Drug Design commissioned by the Com- mitte on Medicinal ... and biological evaluation of these target structures can be used to test and ... inside a macromolecular binding site or comparing several ..... (42) Clark, T. A Handbook of Computational Chemistry; John ..... (96) Beddell, C. R. Chem. SOC.
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Receptor-Ligand Interaction and Molecular Modelling - General
Key words: Receptor-ligand interactions — Drug design — Molecular modeling. Introduction ...... In The Design of Drugs to Macromolecular Targets (Ed C R Beddell) pp 119—. 172, John Wiley and Sons, Chichester. Dean P M (1987) ...
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Structure-based design of enzyme inhibitors and receptor ligands
structure-based drug design is adopting increasing importance in ...... Beddell CR (Ed): The design of drugs to macromolecular targets. John Wiley & Sons ...
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Complex of rat transthyretin with tetraiodothyroacetic acid refined at
hormones and other iodothyronines to human plasma transthyretin; in The Design of Drugs to. Macromolecular Targets (Beddell, C.R., ed.) pp. 120–172, John ...
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NMR and MS Methods for Metabonomics - Springer
Sep 30, 2010 ... In the last decade, metabonomics has become increasingly popular in drug development, molecular medicine, and other biotechnology fields, ...
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Metabonomics: a platform for studying drug toxicity and gene function
Jeremy K. Nicholson, John Connelly, John C. Lindon and Elaine Holmes. INNOVATION ..... induction processes that change the drug-metabolite patterns. As cell death ... Diffusion-ordered and diffusion-edited NMR ... target-organ toxicity or disease fingerprints ..... Anthony, M. L., Beddell, C. R., Lindon, J. C. & Nicholson,.
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(KatG) and S315T mutant from Mycobacterium - Hindawi Publishing
and other drug-resistant strains has increased dramatically [8]. Even though the ..... Carlos Kleber Zago de Andrade for his comments and editing of the manuscript. Finally, we ... [6] Roth, B. and Stammers, D.K., 1992, In: C.R. Beddell (Ed.) The Design of Drugs to Macromolecular Targets. (New York: John Wiley & Sons Ltd.).
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References - Digital Academic Repository - University of Amsterdam
Luz GM, Mano JF (2009) Biomimetic design of materials and biomaterials inspired ... Demers C, Hamdy CR, Corsi K, Chellat F, Tabrizian M, et al. (2002) ... Comparative analysis of macromolecules in mollusc shells. .... New York: John Wiley & Sons. p. 116. ..... biomineralization and potential target of the organotin tributyltin.
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YEAR - Kakatiya University
Navigating with the mouse and keyboard, Entering and editing text, text boxes, text ... how formulas react to worksheet design changes, Auditing tools help spot  ...
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