Meta-analytic Evidence for Familial Coaggregation of Schizophrenia
Jul 10, 2009 ... Study Selection: All family studies published from Janu- ary 1, 1980, to ... a lack of familial aggregation between these 2 disorders is somewhat puz- ... family studies lack an appropriate control group and so cannot be used in ...
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Familial Risk Analysis of the Association Between Attention-Deficit
Oct 1, 1998 ... Family studies also have shown an association between ADHD and PSUD. .... produce evidence for familial coaggregation between the screened conditions and ADHD. ... Our goal in selecting control probands was to satisfy the .... As shown in Figure 1, A, the relatives of group 1 and group 2 probands did ...
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Family study of fibromyalgia - Wiley Online Library
Lesley M. Arnold,1 James I. Hudson,2 Evelyn V. Hess,1 Avis E. Ware,1 .... comparison group of patients with RA was chosen for several reasons. First, the primary rationale stems from our use of a sampling scheme in which we select families with a member .... Familial coaggregation of FM with major mood disorder.
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Multivariate Logistic Regression for Familial Aggregation of Two
The question of whether two disorders cluster together, or coaggregate, within ... to analyze aggregation of two disorders in family studies. ... the typical case- control study, two features of this design ..... not necessary to recruit a group of probands with neither dis- ... Proband selection should minimize the possibility of ascer-.
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Genetic Relationships Between Schizophrenia, Bipolar Disorder
Feb 24, 2014 ... analysis, the familial coaggregation of schizophrenia and ... of bipolar disorder compared with relatives of controls .... commonly occurring genetic variants on the 2 disorders. .... Genomics Consortium Cross-Disorder Group Study of 5 Psychiatric ... picking up association signals in GWAS studies,108 so it.
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Familial Coaggregation of Alzheimer's Disease and Parkinson's
Nov 30, 2013 ... familial coaggregation of these diseases (pooled odds ra- tio, OR: 2.4 ..... The study included 1 group of cases and 2 control groups, 1 hospital based and 1 popula- tion based. ..... Other types of bias include selection and.
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Cross-Disorder Genomewide Analysis of Schizophrenia, Bipolar
Aug 16, 2010 ... Family and twin studies have established that schizo- phrenia ... milial coaggregation for schizophrenia and bipolar disor- ... and control groups was applied, followed .... association across disorders followed by a model selection ap- ... disorder, bipolar II, control]); 3) shared by mood disorders model.
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Longitudinal study of the diagnosis of components of the metabolic
Apr 28, 2010 ... syndrome in individuals with binge-eating disorder. 1–3. James I ... of time (eg, ,2 h), associated with a sense of loss of control over eating. ... In a previous family study that we conducted (11), between. October .... individuals in each group at risk of at least one component, which .... sibility of selection bias.
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Genetic relationships between schizophrenia, bipolar disorder, and
bipolar disorder, with family, twin and adoption studies showing a genetic ... the Kraepelinian dichotomy,2 in which the two disorders were viewed as ... relative prominence of different types of symptom is less clear, and the groups are still .... hierarchical diagnostic analysis, the familial co-aggregation of schizophrenia and ...
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A Controlled Family Study of Anorexia Nervosa and Bulimia Nervosa
evidence that these 2 disorders may have shared familial risk factors. Conclusions: ..... elevated rates among relatives of both ED proband groups, but rates were too low to ..... conclusive.8,10 The familial coaggregation of depression and. EDs may best be .... there were clear advantages to our selection of pure AN and.
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Genetics in eating disorders - SciELO
Sep 14, 2005 ... admixture mapping it is possible to study the genetic structure of admixed human ... the context of inter ethnic groups, and also integrate a new perspective on the .... having the disorders than relatives of unaffected controls.12,25- ... the two disorders, indicating possible shared familial ..... Extreme selection.
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Genome-Wide Association Study of Schizophrenia - National
DNA and clinical data for all cases and controls are or will be publicly available from ... Considerable data suggest SZ is a neurodevelopmental disorder. ... Family studies: co-aggregation of SZ, schizoaffective, other non- ... advocacy/ support groups (NAMI). ... Consensus diagnosis of SZ or SA: after independent review by 2.
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Genetic Boundaries of the Schizophrenia Spectrum: Evidence From
Evidence From the Finnish Adoptive Family Study of Schizophrenia ... The two groups were not differentiated ... noses of 39 index adoptees and comparison subjects from ... The original selection of proband biological mothers was based on hospital ... one had borderline personality disorder (this mother gave two offspring ...
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Selecting control groups for studies of familial aggregation of disease
Selecting control groups for studies of familial aggregation of disease ... or (2) a control group consisting of relatives of individuals without the disease under study. ... group in psychiatric genetics: possible artifactual evidence for coaggregation.
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Family-Based Study Designs
the potential genetic basis of disease using patterns of coaggregation and ... key benefit of family-based association studies is the control for confounding bias due to .... selection, an ascertainment correction must be applied to avoid bias in the ... Linkage occurs when two loci on the same chromosome are inherited together ...
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A genome-wide association study of alcohol-dependence symptom
Oct 23, 2012 ... association results were conducted in two independent samples: nonoverlapping subjects ... Environment (SAGE) and the Australian Twin Family Study of AUDs ( OZALC). ... have previously been associated with risk for bipolar disorder. ... case –control designs, including treatment seeking subjects with.
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Thesis - KI Open Archive - Karolinska Institutet
In Study II, we assessed the co-aggregation of ADHD and overweight/obesity within families and further tested the hypothesis that the familial co-aggregation of the two ... offspring attention deficit hyperactivity disorder: a population-based cohort ...... and control group.118 Both groups are followed by a certain length of time.
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Schizotypy and personality profiles of Cluster A in a group of
Oct 4, 2013 ... their siblings, compared to the healthy controls, showed significant ... Evidence from adoption, twin, and family studies has ..... scores of two Q-factor scales of Personality Disorders of ..... First, selection “bias” may have resulted from the .... prevalence and coaggregation of schizotypy indicators: a multitrait.
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Family history of hematologic malignancies and risk of multiple
Nov 23, 2015 ... And Genetic Epidemiology study of myeloma (259 MM cases; 461 controls) .... Working Group classification criteria for MM. Criteria ... Control selection. Controls ... Centers for Disease Control population databases estab- lished from ..... among MM patients with familial coaggregation of any hematologic ...
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How Health and Disability Laws Hurt Disordered Gamblers
Mar 31, 2012 ... Regardless of how hard he tries to focus on his family and his law practice ... Diagnosdc and Statidcal Manual of Mental Disorders (DSM-II-R). (1987) ... neuroimaging studies, in particular, have begun to delineate the neural circuitry .... within the "Disorders of Impulse Control Not Elsewhere Classified."" 10.
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