Regulation of hematopoietic niches by sympathetic innervation
Regulation of hematopoietic niches by sympathetic innervation. Hector Leonardo Aguila. Summary. Once hematopoiesis is established in the bone marrow,.
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Neural Regulation of Hematopoiesis, Inflammation, and Cancer - Cell
Apr 22, 2015 ... In the hematopoietic system, the ANS regulates stem cell niche homeostasis .... the bone marrow niche, in which sympathetic nerve fibers and.
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Diabetes Gets on the Nerves of the Bone Marrow Niche
in Diabetes (ACCORD) study, cardiovascular autonomic neuropathy has .... Regulation of hematopoietic niches by sympathetic innervation. Bioessays 2006 ...
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Review Series - Blood Journal
Apr 23, 2015 ... sympathetic nerves play a critical role in bone marrow regeneration ... niche and regulate hematopoiesis.53 A mouse fetal bone CD51. +.
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The Adult Hematopoietic Niches — Cellular Composition - InTech
Bone development and the appearance of hematopoietic niches occur ..... myelinated Schwann cells have been identified surrounding sympathetic nerves in BM. .... innervation which down-regulates the CXCL12 expression in the BM in close ...
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Regulation of Hematopoietic Stem Cells - Lund University Publications
Jan 1, 2014 ... This thesis is about the regulation of hematopoietic stem cells ...... Schwann cells, associated with sympathetic nerves in the BM niche, have.
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Signals from the Sympathetic Nervous System Regulate
Jan 26, 2006 ... Hematopoietic stem and progenitor cells (HSPC), attracted by the chemokine ... nervous system regulates the attraction of stem cells to their niche. ...... While it is temping to speculate that sympathetic innervation, which ...
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Hierarchical organization and regulation of the hematopoietic stem
Keywords: Hematopoietic stem cell; Osteoblastic niche. 1. Introduction .... ensheath the autonomic nerves were proposed critical compo- nents of HSC niche [45 ...
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Hematopoietic Stem Cell Niche in Health and Disease
the cells regulating the hematopoietic niche may be reflective of stress ..... not only highly vascularized, but also highly innervated with sympathetic nerves (78).
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Jan 1, 2013 ... Key words bone marrow stem-cell niche, hematopoietic stem cell, mesenchymal stem cell, nestin .... paired sympathetic regulation of osteoblasts30). More re- cently, we .... innervated by sympathetic fibers in the bone marrow.
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Lifestyle Effects on Hematopoiesis and Atherosclerosis
Feb 27, 2015 ... regulate monocyte and macrophage supply in the inflamed vessel wall. ..... the hematopoietic niche.82 Sympathetic nerve fibers run along.
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Regulation of hematopoietic stem cells in the niche
Nov 11, 2015 ... Regulation of hematopoietic stem cells in the niche. ZHAO Meng1 & LI .... linating Schwann cells (glial cells ensheathed autonomic nerves) have been identified as a critical TGFβ signal regu- lator which contributes to TGFβ ...
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The bone marrow niche for haematopoietic stem cells - University of
ponents that regulate HSCs, and to some extent other haematopoietic .... cell types, that is surrounded by a shell of vascularized and innervated bone. a, ..... niches include sympathetic nerves91,92, non-myelinating Schwann cells (which.
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Regulation of hematopoietic and leukemic stem cells by the immune
Jul 4, 2014 ... Signals derived from the HSC niche are necessary to regulate ..... In addition, this microenvironment is innervated by sympathetic nerves fibers ...
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The bone marrow stem cell niche grows up: mesenchymal stem
Mar 14, 2011 ... fied sinusoidal endothelial cells, sympathetic nerve fibers, and cells of the ..... Osteoblastic cells regulate the haematopoietic stem cell niche.
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Megakaryocytes in the hematopoietic stem cell niche
ular cells, sympathetic nerves and Schwann ... megakaryocytes, the hematopoietic cells ... megakaryocytes also contribute to the HSC niche, regulating HSC.
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Minireview: Complexity of Hematopoietic Stem Cell Regulation in
Aug 1, 2014 ... stem cells (HSCs) continuously regenerate the entire blood supply, which is constantly being ... The concept of a hematopoietic niche was first pro- ... sympathetic nervous system; ST-HSC, short-term HSC; WT, wild-type.
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Méndez-Ferrer S, et al. Mesenchymal and haematopoietic stem cells
Aug 12, 2010 ... indicative of a unique niche in the bone marrow made of heterotypic stem-cell pairs. ... tion requires signals from the sympathetic nervous system (SNS)16,17, ... Nestin identifies rare SNS-innervated perivascular stromal cells ..... we provide evidence for a balanced regulation of haematopoietic and.
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The Haematopoietic Stem Cell Niche: New Insights into the
Sep 27, 2011 ... Mechanisms Regulating Haematopoietic Stem Cell Behaviour. Andrew J. Lilly,1 .... Sympathetic Innervation of the HSC Niche. A complex ...
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Deciphering ARAP3 Functions in Hematopoiesis and Hematopoietic
Jan 1, 2015 ... the mesenchymal and osteoblastic BM niche to regulate HSC functions. ...... mesenchymal stromal cells, osteoblasts, sympathetic nerves and ...
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