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Continued - NIDDK Archives - National Institutes of Health
The Worldwide Epidemiology of Primary Liver Cancer. Javier Bosch, Institut ... Hepatitis B and HCC. Christian Brechot, INSERM, France .... The predominant role of environmental factors in the etiology of. LC is strongly ... Liver Cancer. In: Tabor E. (ed.) .... inhibit progression to cirrhosis of the liver and HCC; and establishing.
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Structure and expression of Tg737, a putative tumor suppressor
primary liver cancer. In: Bréchot C, ed. Primary Liver Cancer: Etiological and Progression Factors. Boca Raton: CRC Press, 1994:269-277. 7. Henkler F ...
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Excess Risk of Primary Liver Cancer in Patients With Diabetes Mellitus
Hans-Olov Adami, Wong-Ho Chow, OlofNyren, Christian Berne, ... of primary liver cancer in developing countries, but risk factors ...... adapted for indexing of hospital records, 6th ed.). ... Alcoholism and liver cirrhosis in the etiology of primary.
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Full-Text PDF - MDPI
Nov 9, 2009 ... and Christian Trepo ... That might be explained by the multiplicity of etiologic factors, the ... heterogeneity of tumors bulks and the ignorance of the liver cell types that .... modeled by enforcing the expression of oncogenes in primary cells. .... progression and DNA hyper-replication in a context of immortality, ...
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Nutrition and Hepatocellular Cancer - Karger
Nov 18, 2015 ... Kerstin Schütte Christian Schulz Peter Malfertheiner. Department of ... resenting more than 90% of primary liver cancers. ... eral factors impact on the prognosis of patients with HCC, including tumor-related factors, liver ... To prevent disease progression to liver cirrhosis or HCC in patients with nonalco-.
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Identification of human cancer-related genes by naturally occurring
expressed in human liver and cancer tissues; and (6). Nuclear Matrix ... HCCs allow to identify cellular genes involved in cancer. We therefore ... HBV genome is a major risk factor for HCC. Besides ..... liver cancer: Etiological and progression factors. BreÂchot C (ed). CRC ... Primary liver cancer: Etiological and progression ...
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Noninvasive assessment of liver fibrosis: The clinical context and
affect risk and progression of chronic hepatitis B virus infection. HEPATO- ... liver tumor-initiating cells drive self-renewal and tumor initiation ... Christian Medical College ..... Metabolic Syndrome is Also a Risk Factor for Primary Liver Cancer in Patients Younger .... Hepatitis viruses, alcohol, and tobacco in the etiology of.
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Mutations of the HFE Gene in Patients With Hepatocellular Carcinoma
Susanne Rasoul-Rockenschaub, M.D., Christian Müller, M.D., Friedrich Wrba, M.D., ... mon malignant tumors worldwide. ... irrespective of the etiology of the underlying liver disease seems to be the most important risk factor for HCC (3, 4). ..... primary liver cancer in cirrhosis in Austria—etiological con- .... of the liver, 2nd ed.
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Hepatic fibrosis: Concept to treatment - ScienceDirect
Apr 22, 2015 ... Macrophages are the fuel and brake of liver fibrosis progression and resolution. .... and the ECM that they produce are primary targets of antifibrotic therapies. ... on the etiology of liver disease and its stage: 1) perisinusoidal/vascular ... [38]); ROS, reactive oxygen species; TNFα, tumor necrosis factor α; Shh, ...
[ 1-s2.0-S016882781500149X-main.pdf?_tid=02a9044e-fe31-11e4-a526-00000aacb35d&acdnat=1432044899_67c4596406ef95d0d01c0d93cf3ad3f4 - Read/Download File

Nonalcoholic Fatty Liver Disease - Perelman School of Medicine
clinical outcomes, ranging from benign hepatic steatosis to cirrhosis. ... management. For patients with NAFLD at risk of disease progression, there is a lack of large, .... Weber–Christian disease .... so that the diagnosis of primary NAFLD can be made re- ..... The expression of tumor necrosis factor in human adipose tissue.
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Allele loss and epigenetic inactivation of 3p21.3 in malignant liver
Feb 9, 2005 ... Christian Wittekind1, Ulrich R. Hengge3 and Andrea Tannapfel1* ... Primary liver cancer is one of the most frequent carcinomas ... alcoholic cirrhosis, whereas in 2 patients the etiology of the cir- ..... fore, loss of RASSF1A may contribute to tumor progression by ... Scatter-factor and semaphorin receptors:.
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Report - IARC
WORLD CANCER REPORT. Edited by. Bernard W. Stewart. Paul Kleihues. IARCPress ... Kola Okuyemi. Christian Partensky ... already been shown to prevent liver cancer in high-incidence countries and it is likely that HPV vaccination will .... ence to etiological factors. For example, ... Cancer has played a primary role in the.
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Full Text (PDF) - Radiology - RSNA
Dec 12, 2003 ... Christian Müller, MD ... ing to the Barcelona Clinic Liver Cancer (BCLC) staging ... to progression was similar between the two treatment ... primary tumor in the liver with TACE might be ... I.G., W.S.; and manuscript editing, M.P., I.G., W.V., A.M., ..... Univariate Analysis of Prognostic Factors for Overall Survival.
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EASL clinical practice guidelines on the management of benign liver
Apr 5, 2016 ... Benign liver tumours are a heterogeneous group of lesions with ... These may include a previous cancer or constitutional ... In addition, direct questioning should identify any risk factors for ... Hepatic haemangiomas are the most common primary liver ...... pattern of progression (evidence level III, grade of.
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Biology and Molecular Aspects of Development and Progression of
MOLECULAR BASIS OF BLADDER CANCER PROGRESSION. CONCLUSION ... under the influence of specific etiologic factors. In order of ... treated for their primary component. .... in this process is N-oxidation catalyzed by hepatic cytochrome P450 1A2 ...... Christian BJ, Kao CH, Wu SQ, Meisner LF, Reznikoff CA. EJ/ras ...
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Associations of VEGF-C Genetic Polymorphisms with - Plos
Mar 7, 2014 ... 3 Cancer Research Center, Changhua Christian Hospital, Changhua, Taiwan, ... Background: Vascular endothelial growth factor (VEGF)-C is associated with .... reported to be correlated with the risk of oral [16] and liver ... the cases, including TNM clinical staging, the primary tumor size, ..... etiology of UCC.
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DNA methylation markers and serum α-fetoprotein level are
Dec 12, 2014 ... are prognostic factors in hepatocellular carcinoma ... Department of General Surgery, Changhua Christian Hospital, ... (RASSF1A) genes in tumor specimens from 50 patients with HCC. ..... ed RASSF1A promoter regions had a better progno- .... Bosch FX, Ribes J, Díaz M, Cléries R. Primary liver cancer:.
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Full Text (PDF)
Jan 15, 2013 ... The molecular etiology of human progenitor reprogramming into self-renewing leukemia stem ... adenosine-to-inosine RNA editing during CML progression. Lenti- ... promotes expression of the myeloid transcription factor PU.1 and induces ... sponsive ADAR1 expression in LSC from primary BC CML pa-.
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Safety Evaluation — Food & Chemical - Toxicologic Pathology
Mutations of ras Protooncogenes and p53 Tumor Suppressor Gene in Cardiac ... example, in liver hemangiosarcomas from vinyl chloride- .... ed conformational polymorphism analysis (SSCP) was ... dilution of the primary polyclonal rabbit antibody CM-5 .... progression of pulmonary tumors induced by 4-( methylnitrosami-.
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Lamivudine for Patients with Chronic Hepatitis B and Advanced
Oct 7, 2004 ... The primary end point was time to disease progression, defined by hepatic decompensation, hepatocellular ... Continuous treatment with lamivudine delays clinical progression in patients with chron- .... holism, uncontrolled diabetes, or cancer), pancre- ..... the factors other than treatment that significantly.
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