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The mammalian nonsense-mediated mRNA decay pathway: To
Feb 4, 2009 ... Nonsense-mediated mRNA decay (NMD) degrades mRNAs carrying premature translation termination codons (PTCs). Although the core ...
[ 1-s2.0-S0014579309000155-main.pdf?_tid=bf3019f2-1f31-11e4-97e9-00000aab0f6c&acdnat=1407526105_5c0914e378b4a23f909188e469e0b22a - Read/Download File

Nonsense-mediated mRNA decay in humans at a glance
Nonsense-mediated mRNA decay (NMD) is an mRNA quality-control mechanism ... different 5′-cap-binding proteins typify mRNAs undergoing NMD? How can ...
[ 461.full.pdf - Read/Download File

Leveraging Rules of Nonsense-Mediated mRNA Decay for Genome
Jun 2, 2016 ... Nonsense-mediated mRNA decay (NMD) is a eukaryotic mRNA quality ... protein synthesis and mRNA quality inspection via NMD, a pro-.
[ S0092-8674(16)30656-0.pdf - Read/Download File

Nonsense-mediated mRNA decay factors act in - Ivica Letunic
Nonsense-mediated mRNA decay (NMD) is a surveillance pathway that ... proteins act mainly in the NMD pathway and their role in mRNA decay has not ...
[ 16199763.pdf - Read/Download File

The Coupling of Alternative Splicing and Nonsense‑Mediated
by the nonsense‑mediated mRNA decay (NMD) pathway. ... may link alternative splicing and NMD to regulate the abundance of mRNA transcripts. This.
[ lareau-2007-landes-nmd.pdf - Read/Download File

Nonsense-Mediated mRNA Decay: Degradation of Defective
Oct 2, 2015 ... Abstract. Nonsense-mediated mRNA decay (NMD) is a eukaryotic surveillance mech- anism that monitors cytoplasmic mRNA translation and ...
[ annurev-genet-112414-054639 - Read/Download File

Nonsense-mediated mRNA decay - Biochemical Society Transactions
Translation and mRNA decay are coupled processes; the link is most obvious in the case of NMD (nonsense- mediated mRNA decay). NMD is a mechanism that  ...
[ 514.full.pdf - Read/Download File

Regulation of Natural mRNAs by the Nonsense-Mediated mRNA
The nonsense-mediated mRNA decay (NMD) pathway is a specialized mRNA degradation pathway that degrades select mRNAs. This pathway is conserved in  ...
[ 1126.full.pdf - Read/Download File

Nonsense-mediated mRNA decay: novel mechanistic insights and
Nonsense-mediated mRNA decay (NMD) was originally coined to define a qual- ... according to which NMD ensues on mRNAs that fail to terminate translation.
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SURVEY AND SUMMARY Mechanism and regulation of the
Jan 14, 2016 ... The Nonsense-mediated mRNA decay (NMD) path- way selectively degrades mRNAs harboring prema- ture termination codons (PTCs) but ...
[ nar.gkw010.full.pdf - Read/Download File

Nonsense Mediated mRNA Decay (NMD) Mechanism in Drosophila
Abstract: Nonsense-mediated mRNA decay (NMD) is a mechanism that prevents the accumulation ... mechanism is involved in the rapid degradation of mRNA.
[ SUB1592.pdf - Read/Download File

Nonsense-mediated mRNA decay - Case Western Reserve University
DSE downstream sequence element. EJC exon–exon junction complex. mRNP messenger ribonucleoprotein particle. NMD nonsense-mediated mRNA decay.
[ Baker and Parker, 2004.pdf - Read/Download File

Nonsense-mediated mRNA Decay - Cold Spring Harbor Symposia
Nonsense-mediated mRNA decay (NMD), also called. mRNA surveillance, is ... human (h) Upf proteins known to function in NMD, and we use this information to  ...
[ 313.full.pdf - Read/Download File

New insights into the formation of active nonsense- mediated decay
In the nonsense-mediated mRNA decay (NMD) path- way, an exon-junction protein complex (EJC) and hUpf proteins mediate rapid downregulation of aberrant.
[ NMD-TiBS.pdf - Read/Download File

No Nonsense: The Protection of Wild-Type mRNAs From Nonsense
Apr 8, 2016 ... mRNAs From Nonsense-Mediated mRNA Decay ... Wild-type mRNAs with NMD- targeting signals, which include 1) a translated uORF, 2) a.
[ viewcontent.cgi?article=1082&context=bioscidiss - Read/Download File

Nonsense-mediated mRNA decay modulates clinical - Nature
Jun 7, 2006 ... The nonsense-mediated decay (NMD) pathway is an mRNA surveillance system that ... eliminates NMD and prevents the normally rapid decay.
[ 5201649a.pdf?origin=publication_detail - Read/Download File

Spermatogenesis Studies Reveal a Distinct Nonsense-Mediated
May 5, 2016 ... PERSPECTIVE. Spermatogenesis Studies Reveal a Distinct. Nonsense- Mediated mRNA Decay (NMD). Mechanism for mRNAs with Long 3. 0.
[ Mühlemann_PLoS Genetics Perspective_2016.pdf - Read/Download File

Chapter 5 Nonsense-mediated mRNA decay is a regulator of - FTP
furthering our understanding of nonsense-mediated mRNA decay (NMD). ... exons that lead to NMD-targeting on inclusion (Lareau et al., 2007; Ni et al., 2007 ;.
[ chapter5.pdf - Read/Download File

Stop that nonsense! | eLife
Sep 9, 2014 ... MicroRNA-mediated repression of nonsense mRNAs. ... cells have evolved methods known as nonsense-mediated decay (or NMD for short) to ...
[ elife-04300-v1.pdf - Read/Download File

Nonsense-mediated decay: linking a basic cellular process to
mechanisms, among which nonsense- mediated decay (NMD) is perhaps the best studied. NMD ensures destruction of mRNAs that harbor premature ter-.
[ erm.09.18 - Read/Download File

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