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Motor patterns in Parkinson's disease: A datadriven approach
Apr 7, 2009 ... Motor Patterns in Parkinson's Disease: A Data-Driven Approach. Stephanie M. van Rooden, MSc,* Martine Visser, PhD, Dagmar Verbaan, MSc,.
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Patterns of Cortical Thinning in Nondemented Parkinson's Disease
driven approach based on cortical thickness data. Methods: T1-weighted .... recruited from the Parkinson's Disease and Movement. Disorders Unit, Hospital ...
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Heterogeneity of Parkinson's disease in the early clinical - BMJ
Jun 10, 2004 ... Methods: Data on demographic, motor, mood, and cognitive measures were collected from 120 ... This data driven approach for defining heterogeneity in PD .... generally similar patterns for patient clusters and consistent.
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Clinical subtypes of Parkinson's disease - Residency Programs
Nov 16, 2010 ... Data of motor and nonmotor PD symptoms were col- lected in 802 patients in two ... PD, by using a data-driven approach applied to the data of two large ..... Patterns of motor and non-motor features in Parkinson's disease. J.
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Parkinson's disease severity and motor subtype influence physical
Abstract—The severity of Parkinson's disease (PD) and PD's motor subtypes influence the components of ..... Parkinson's disease patients show different patterns of FP- ... disease in the early clinical stages using a data driven approach.
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Parkinson's Disease Subtypes in the Oxford Parkinson Disease
Objective: Use a data-driven approach to unravel any heterogeneity in the ... Keywords: Parkinson's disease, Cohort studies, cluster analysis, factor analysis ... such as the division of subjects by motor phenotype and age of onset [2, 3]. Unfortunately, this approach relies on accurate clinical observation to recognise patterns.
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Clinical heterogeneity in patients with early-stage Parkinson's
Clinical data on demographics, motor variables, motor phenotypes, disease progression, global ... defines clinical heterogeneity of PD patients in early stages using a data-driven approach. The subtypes ...... In the studies of PD motor patterns.
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The Heterogeneity of Early Parkinson's Disease: A Cluster - Plos
Aug 1, 2013 ... motor symptoms in a large cohort of newly diagnosed untreated PD patients. ... Results: The data driven approach identified four distinct groups of patients, we have labeled: ..... with the BPM a similar pattern of motor disability.
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first-principle data-driven models for assessment of motor disorders
Apr 16, 2014 ... non-motor symptoms of PD advance with the disease progression ... Current technologies for at-home PD treatment are based on data-driven approaches for ...... tionship between patterns of input attributes (predictors) and ...
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Review - Environmental Health Perspectives - National Institutes of
Research on the Premotor Symptoms of Parkinson's Disease: Clinical and. Etiological ...... 2009. Motor patterns in Parkinson's disease: a data-driven approach.
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The Factor Structure of the UPDRS as an Index of Disease
Data was derived from a representative cohort of 122 PD patients followed ... motor section of the UPDRS (UPDRS-3) which has ... This data-driven, hypothesis-free approach allows an ... pattern matrix evaluated with factor loadings of <0.4.
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Research Article Relation of Subjective Quality of Life to Motor
Parkinson's disease (PD) presents with extensive heterogeneity in symptomatology, inviting ..... in the early clinical stages using a data driven approach,”.
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Parkinson Subtypes Progress Differently in Clinical Course - Plos
Oct 8, 2012 ... Course and Imaging Pattern ... Objective: To elucidate whether Parkinson's disease (PD) subtypes show a ... data regarding the differences in dopaminergic uptake at a given ... patients would show a stronger decline in their motor functions. .... driven ''small volume approach'' for the SPM analysis and.
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Regional CBF changes in Parkinson's disease - Swartz Center for
Apr 17, 2007 ... motor Unified Parkinson's Disease Rating Scale scores correlated ... on disease- related changes in patterns of functional con- nectivity [10, 11]. ... iate approach, is a recently developed data-driven approach to imaging data ...
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Identifying the Clusters within Nonmotor Manifestations in - Plos
Mar 18, 2014 ... Background: Classical and data-driven classifications of Parkinson's disease (PD ) are ... Methods: Clinical data on demographic, motor and nonmotor features, ... PD patients and two nonmotor clusters in de novo PD patients, without a .... unsupervised hierarchical approach is that it can be applied when.
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Depression and anxiety subtypes in Parkinson's disease - Hal
Jul 8, 2011 ... Parkinson's disease, depression, anxiety, heterogeneity, latent class analysis ... motor and cognitive domains, with implications for pathophysiology and outcome. ... distinct patterns of association with important demographic and clinical ... use of a data-driven approach to explore possible heterogeneity in ...
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Time to redefine PD? Introductory statement of the MDS Task Force
International Parkinson and Movement Disorder Society ..... little difference in clinical evolution patterns.20. 6. Similar ... One uses data-driven approaches with.
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Distinguishing the Central Drive to Tremor in Parkinson's Disease
Jan 14, 2015 ... Parkinson's disease (PD) and essential tremor (ET) are the two most common movement disorders. ... These patterns are reflected in the tremors' derived frequency ... motor system, affecting patients' ability to perform activities of ...... We adopted an integrated and data-driven approach to explore the.
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Automatic Spiral Analysis for Objective Assessment of Motor - DiVA
Sep 17, 2015 ... limb movement data of 65 advanced PD patients and 10 healthy .... In this paper, we propose a data-driven method for objective recognition and classification of PD ... motor symptoms of the patients, a data visualization approach was ..... distinguishing between movement patterns exhibited by PD patients ...
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PD Disease State Assessment in Naturalistic Environments Using
People affected by PD show a variety of motor features that gain in severity with the .... driven research represents a significant barrier towards prac- tical assessment ... PD. Instead of bas- ing the development of our approach on data collected in ..... lar patterns of fluctuation compared to the diary entries for each participant.
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