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Molecular Mechanisms of Bacterial Virulence: Type III - NCBI
by a distinct molecular mechanism. However, the spectrum ... The Yersinia proteins are the components of a novel ... In gram-negative bacteria, these proteins must pass ... Figure 1: Schematic diagram of type I, type II, and type III secretion systems. All systems ...... Molecular Biology of Bacterial Infection: Current. Status and ...
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virulence mechanisms of pathogenic yersinia - DiVA
DEPARTMENT OF MOLECULAR BIOLOGY, UMEÅ UNIVERSITY, SWEDEN ..... 3.3.5 A model of substrate specificity switching by YscP and YscU..40 .... secretion systems of Gram-negative bacteria are reviewed below (chapter 1.3), with ... transmission and pathogenesis of Y. pestis is reflected in dramatic changes within.
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Yersinia enterocolitica pathogenesis - Wiley Online Library
1Department of Microbiology and Molecular Genetics and ... Yersinia pathogenesis the total contribution of chromoso- .... murine model of infection. ..... transposon mutagenesis in Gram-negative bacteria. Bio- technology 1: 784–791. Southern ...
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Structural biology of bacterial pathogenesis
structural understanding of the various Gram-negative ... 1Institute of Structural Molecular Biology, 2School of Crystallography, .... pathway models: hemolysin secretion for type I secretion; P pili assembly for the chaperone-usher pathway; NalP for the type .... structurally related adhesins Yersinia pseudotuberculosis invasin.
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Adhesive properties conferred by the plasminogen - Microbiology
provided by H. Wolf-Watz, Department of Cell and Molecular. Biology, University of Umei, Sweden. ..... Yersiniae : A Model for Gram-negative Pathogenesis.
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Phospholipase A in Gram-negative bacteria and its role in
Biotechnology and Environmental Biology, School of Applied Sciences, RMIT ... involvement of PLA in bacterial invasion and pathogenesis. ... on PLA as a virulence factor in Gram-negative bacteria. ... encoding a phospholipase with a predicted molecular mass .... In this model, OMPLA traverses the outer membrane 14.
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Characterization and Biological Role of the O-Polysaccharide Gene
Apr 19, 2007 ... Yersinia enterocolitica serotype O:9 is a gram-negative enteropathogen that infects animals and humans. ... Pathogenesis of these strains is associated with the presence of ... Present address: Molecular Cancer Biology Program, 00014 Uni- ...... The yersiniae—a model genus to study the rapid evolution.
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Yersinia pseudotuberculosis: Evidence for a - Journal of Bacteriology
Department of Cell and Molecular Biology, University of Umea, S-901 87 Umea,' and. Department .... Yersinia as a Model for Pathogenesis of Gram-Negative.
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Investigation into the role of the serine protease HtrA in Yersinia
a Pathogen Molecular Biology and Biochemistry Unit, Department of Infectious and Tropical ... mutants are attenuated in the animal model and can be used as live vaccines. ... Keywords: HtrA; Isogenic mutant; Pathogenesis; Stress response ; Yersinia pestis. 1. ... Gram-negative pathogens are attenuated and act as live.
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Patterns of Pathogenesis - Molecular and Cell Biology - University of
ogen-associated molecular patterns (PAMPs) and the host receptors that ... bacterial lipoproteins, from Gram-positive and Gram-negative bacteria, which are .... The PAMP model is also complicated by the extent to which pathogens can modify .... as Yersinia can utilize T3SSs to deliver effectors that block uptake of bacteria ...
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Full Text (PDF)
Jul 12, 2011 ... Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390 ... sion on the outer membrane of a Gram-negative pathogen is necessary for virulence in a nematode infection model and for ef- .... pathways is a key step in the pathogenesis of many Gram-negative.
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Invertebrates as animal models for Staphylococcus aureus
Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield S10 2TN, UK. Received 1 November ... any host to qualify as a model for bacterial pathogenesis ... The gram-positive bacterium Staphylococcus aureus is ..... typhimurium [79], Serratia marcescens, [22] and Yersinia. [80].
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Bacterial Adhesion: Chemistry, Biology and Physics (Advances in
But why this particular book when reviews on bacterial pathogenesis are com ... though, biochemical and structural biology knowledge of the molecular ... pathogens discussed in the biology section, again from both Gram-negative and ..... nificant pathogens in their own right, the yersiniae have been used as model systems.
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Bacterial iron acquisition in the host environment.
point of pathogenesis and invasiveness: eukaryotic hosts sequester iron as a defense ... Gram-negative bacteria, like Escherichia coli, Salmonella typhi,. Vibrio cholerae, Yersinia pestis, and Neisseris meningitidis contain redundant, ... The molecular biological strategy of allelic exchange to create chromosomal deletions.
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Standard PDF (234.8 KB) - Wiley Online Library
infection model, an inv mutant has a wild-type LD50, even though ... Yersinia enterocolitica is a Gram-negative enteric human pathogen that ... critical first step in the pathogenesis of Y. enterocolitica infections. ...... Molecular Biology, 2nd edn.
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Virulence Factors of Gram- Negative Bacteria in Sepsis with - Karger
Gram- negative bacteria causing human sepsis with a focus on Neisseria ... pathogenesis of iron acquisition, bacterial secretion systems, quorum sensing, ... Francisella tularensis and Yersinia pestis have acquired greater recent ..... high levels of IL- 10 in animal models. ..... and molecular biology of Neisseria meningitidis.
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model of infection. Yersinia enterocolitica in a BALB/c mouse
Pathogenesis of Defined Invasion Mutants of Yersinia ... Department of Microbiology & Molecular Genetics1 and Molecular Biology Institute,3 University of California ...... gram-negative coccobacillary forms near the center of the ne- crotic foci.
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Studying Salmonellae and Yersiniae Host–Pathogen Interactions
Aug 9, 2012 ... transcriptional regulatory and start sites, and (4) molecular biology tools ... strategies, not only for these specific pathogens, but also for related gram- negative ..... models of Yersinia and Salmonella pathogenesis will have ...
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Pathogenicity islands: a molecular toolbox for - Wiley Online Library
Aug 24, 2006 ... both Gram-positive and Gram-negative bacterial pathogens of .... Therefore, a subset of PAIs of some pathogens like H. pylori, Yersinia ... According to the model of Hacker and Carniel (Hacker and Carniel ... The molecular biology and the evolution of pathogenicity islands 1709 ...... bacterial pathogenesis.
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The Pathogenesis of-Campylobacter jejuni-Mediated Enteritis
Campylobacter jejuni, a gram-negative spiral shaped bacterium, is a frequent .... advanced texts in microbiology, molecular biology and medical research. Full details ..... hypothesized that the lack of pathology in the mouse model was a result of the ..... pathogenesis of Yersinia (Schmiel et al., 1998), the precise role of these ...
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