Control of sulphate assimilation and glutathione synthesis
Key words: Glutathione synthesis, nitrate deficiency, nitrate reduction, sulphate ..... the molecular mechanism of regulation of sulphate assimi- lation by sulphur ... The effects of nitrogen nutrition on sulphate assimilation were corroborated by ...
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Regulation of glutathione synthesis in leaves of transgenic poplar
regulation of sulfur nutrition and in the tolerance to various forms of stress ( Alscher, .... Effect of glutathione precursors 0n the time-course of glutathione accumulation in leaf ... between the factors that may control glutathione synthesis in the presence of .... Mechanisms (Alscher, R.G. and Cumming, J.R., eds). NY: Wiley-.
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Polyphenols and glutathione synthesis regulation1– 4
mediated regulation of glutathione alters cellular processes. Evi- dently ... A possible mechanism for the protective effects of fruits and vegetables with respect to ... 4 Address reprint requests to R Blomhoff, Institute for Nutrition Research,. Faculty of .... dimethylsulfoxide (DMSO), or with dimethylsulfoxide as a control, for 17 h.
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Advances in Sulphur Amino Acid Nutrition - The Poultry Federation
The first use of dietary amino acids is as building blocks for protein synthesis for muscle .... incubation with HMTBA compared to control medium led to increase enzyme ... reflect a different mechanism underlying the effect of H2O2 and TNF-α on .... glutathione synthesis in the cell and that adequate sulphur amino acid ...
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Manipulation of Glutathione and Amino Acid Biosynthesis in the
Laboratoire du Métabolisme et de la Nutrition des Plantes (G.N.), and ... chloroplastic up-regulation of GSH synthesis is associated with an ... exert their effects on glutathione content. ... ered this inhibition to be a feedback control mechanism.
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Recent Advances on the Nutritional Effects Associated - Journal of
Further research is required to clarify the mechanisms of inhibition of cellular ... glutathione S-transferase; NF-B, nuclear factor B; PAP, prostatic acid phos- ... ( GSH) synthesis. ... the control of proliferation and cell cycle regulation (Ziegler.
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Recent Advances in Nutritional Sciences Glutathione Metabolism
nutrient metabolism, and regulation of cellular events (in- cluding gene .... synthesis. -Glutamylcysteine synthetase is the rate-control- ling enzyme in de novo synthesis of GSH (8). Knowledge .... two mechanisms: 1) the uptake of cystine, and 2) the preven- ... has an important effect on protein nutrition and therefore on.
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Effect of whey protein isolate on intracellular - Essential Nutrition
Effect of whey protein isolate on intracellular glutathione and ... significantly increased intracellular GSH by 64%, compared with control cells receiving no hydrolyzed WPI (P<0.05). ... The results of this study indicate that WPI can increase GSH synthesis and protect ... primary cellular mechanisms are involved in maintain-.
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Implications for GI, Immune, and Neuronal Function in Autism
metabolic and nutritional environment, whereas postnatal epigenetic programming (PEP) importantly depends upon .... regulatory mechanism not only controls ROS formation but .... The amino acid cysteine is rate-limiting for glutathione (GSH) synthesis and ... their growth-promoting effects, which are associated with.
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Glutathione in Cancer Cell Death - MDPI.com
Mar 11, 2011 ... activity are the rate-limiting factors in GSH synthesis . ... Cellular redox balance control regulatory pathways determining cell viability. .... Glutathione and the Mechanisms of Cancer Cell Death .... many antioxidants can exert direct effects upon several signal transduction enzymes independently of.
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PATHWAYS AND REGULATION OF SULFUR METABOLISM
Mar 17, 2000 ... has allowed many of the enzymes and regulatory mechanisms involved in .... for methionine, protein, and glutathione synthesis. ... regulated at the mRNA level by changes in the sulfur nutritional .... are controlled by O-sulfation (131). .... effects on expression of sulfate transporters and assimilation enzymes.
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Nutritional and Metabolic Aspects of Glutathione - Annual Reviews
EFFECT OF DIETARY CONSTITUENTS ON GLUTATHIONE METABOLISM . .. .. 293 ... The synthesis o f glutathione proceeds in two steps (39, 94). Unlike in the ... y-glutamylcysteine synthetase, acts as an ef fective feedback control for the regulation o f ... enzymatic mechanism exists for the reduction o f GSSG to GSH.
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Gene cloning: Studies of nutritional regulation of gene expression
function, both normal and pathological: many nutritional and dietary effects on ... to modulate the expression of genes and, thus, the extent of synthesis of specific proteins. .... glutathione peroxidase (EC 184.108.40.206) and phospholipid peroxidase ( EC 220.127.116.11) by ... Mechanisms of nutritional control of gene expression.
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Effect of Prolonged High-Fat Diet on Thiol-Disulfide Homeostasis in
Keywords: high-fat diet; thiol-disulfide homeostasis; redox-glutathione system. ... of the thiol-disulfide regulation has attracted much attention . ... between glutathione levels and nutrition. ... related to the establishment of the mechanism of the influence of ... 0.001 and MDA: P<0.01) relative to the control group (Table 3).
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24 Gastrointestinal protein and amino acid metabolism in - Elsevier
first tissue exposed to the diet, it has a key regulatory role in the digestion, absorption ..... over, gut protein synthesis rates are modulated by several nutritional and hormonal .... of nucleic acids, nucleotides, amino sugars, amino acids, and glutathione ... chemical mechanism whereby glutamine affects intestinal function may.
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The Antioxidant Role of Glutathione and N-Acetyl- Cysteine
1Exercise and Sport Nutrition Laboratory and the 2Exercise and Biochemical Nutrition ... minimize the detrimental effects of oxidative stress that are commonly ... mechanisms: 1) mitochondrial origin in which free .... deoxyribonucleotide synthesis, regulation of immune .... transduction of redox control parameters of the cell.
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Nutrition, Sleep and Sleep Disorders – Relations of Some - InTech
Different nutritional factors, and eating, can have an effect on the CNS by different ... Substances involved in the sleep-wake regulation and food intake .... immediately released and exert their actions on cells in the vicinity of their synthesis . PGs ... Measuring glutathione levels in specific areas of the brain of sleep-.
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modulating and monitoring intracellular - Ideals
mechanisms that mediate redox environment are poorly understood largely .... 2.3 The Glutathione / Glutathione Disulfide Redox Couple GSH/GSSG . ..... synthesis phase ..... 80, 81), yet the type of “controlled redox regulation” observed in normal cells does ... effects of nutrition, Mutation Research-Genetic Toxicology and ...
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Effect of Nrf2 activators on release of glutathione, cysteinylglycine
The rate of GSH synthesis is controlled largely by the activity of γ-glutamyl cysteine ligase. ... Once in the nucleus, Nrf2 binds to antioxidant response elements (ARE) present in the regulatory ..... Molecular mechanism of the regulation of glutathione synthesis by tumor ... Asia Pacific Journal of Clinical Nutrition, 17 (Suppl.
[ 1-s2.0-S2213231713000645-main.pdf?_tid=075ee996-5d77-11e4-b44b-00000aacb35f&acdnat=1414372833_0b596913c438365cc9345677f30f2b0b - Read/Download File
Depletion of Glutathione during Oxidative Stress and Efficacy of N
Jan 26, 2015 ... uptake, storage and formation of ammonia, the homeostatic control ... The synthesis of glutathione involves the uptake and release of ... most sought after antioxidant for most cellular mechanisms showing ... of the nutritional regulation of GSH metabolites is critical to improve health and treat these diseases.
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