Fluorine Containing Heterocycles Part 11 56 Fluoro 65 X Benzofuroxans Related PDF's

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Download Sample pages 1 PDF - Springer
56. 57. 58. 59. Synthesis of Nitrobenzazoles. The enormous amount of ... tives that are a part of so-called universal nucleosides [9]. ... by-product is observed [ 11]. ..... been established [161] that fluoro-containing benzofuroxans are fairly easily ... Under nitration conditions the substituted fluorine (or the amine group) in the.
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Download Sample pages 2 PDF - Springer
Dec 19, 2013 ... Benzisoxazole Á Carbanions Á Heterocycles Á Hydroxylation Á Indole .... substitution of halogens X, the SNAr process, is just a secondary ... when nucleophiles contain nucleofugal groups L at the nucleophilic .... *product of SNAr of fluorine .... phenyl sulfone was reacted with quinoxaline (Scheme 11). [ 65].
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Р-01 REACTIONS OF POLYFLUOROAROMATIC - Fluorine Notes
It is shown that reactions of polyfluoroaromatic compounds, containing a –N=CCl group ... synthesis of the fluorinated 5- and 6-membered N-heterocyclic derivatives. ..... H2NOC. F. 58 %. 60 %. 69 %. 56%. 83%. 68%. NHAc. CF3. F. Zn. NH3-H2O ..... Data of crystal X-ray analysis demonstrate that esters II have Е- isomer form.
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Get PDF (2016K) - Wiley Online Library
I-Acyl-I-benzazepine, 65 ... Chemistry of Heterocyclic Compounds, Volume 43 ... acetylenedicarboxylic ester condensation,. 54-56. Azepinobenzimidazole, dihydro, 49- ... 6H-Azepino[ 1,2-a]benzimidazole, X ... N-acetyl derivative, 110-1 11 .... treatment with hydrogen fluoride-sulfur ..... sulfur-containing derivatives, 445-446.
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1-(2', 4', 6'-Trinitrophenyl) imidazoles and-1, 2, 4-triazoles as
Mar 23, 1994 ... m/s, but it was quite sensitive, with a drop height of 11 cm, and it proved ... contains the "trigger linkage" at which the initiation reaction occurs ... or X = N, Y = CNO 2 ... treatment with picryl fluoride at ambient temperature, followed by ..... in part to the highly acidic nature of the parent heterocycles, but is also.
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Synthesis and structureeactivity relationship of 3-phenylquinoxaline
The most interesting compounds are 7-(methyl or methoxy)-3-(40-fluoro or ... many mono- and di-N-oxide derivatives of this heterocyclic ... by new substituents such as: a fluorine atom (sp ¼ 0.06; 17e .... ii. Series I. 1-48. Scheme 2. Synthesis of quinoxaline-2-carbonitrile, ethyl ..... A. Monge, Pharmazie 56 (2001) 205e207.
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Novel quinoxaline 1,4-di-N-oxide derivatives as new - Dadun
fluoro groups at the 6- and 7-positions of the quinoxaline ring, was the most active and selective ... heterocycles, empirically discovered over three decades ago. ... and it was also observed that benzofuroxan derivatives containing N- oxide cause a .... derivatives substituted by fluorine in C-6 and C-7 of the quinoxaline ring ...
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Abe D., Sakaki T., Kusudo T., Kittaka A., Saito N., Suhara Y
Andersson S., Hofmann Y., Nordling A., Li X., Nivelius S., Andersson T.B., ... Aprile S., Del Grosso E., Grosa G. In vitro and in vivo phase II metabolism of ... Lakshmi V.M., Wickstra J., Hsu F.F., Zenser T.V. Metabolism of a heterocyclic amine colon ... and role of human cytochrome P450 and flavin-containing monooxygenase.
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