Effect of microstructure on hydrolytic degradation studies of poly (l
Volume 94, Issue 9, September 2009, Pages 1364–1372. Cover image. Effect of microstructure on hydrolytic degradation studies of poly (l-lactic acid) by FTIR ... of lactic acid obtained by HPLC showed that the alkaline hydrolysis of PLLA films ...
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Influence of macromolecular structure of novel 2-and 4-armed
Jun 7, 2016 ... To achieve this, novel 2- and 4-armed PDLLA and PLLA (noted as 2b and 4b) were .... PLLA . They also investigated the hydrolytic degradation and thermal prop- ... determined by modular system Agilent 1200 series HPLC ..... Vasanthan N, Ly O (2009) Effect of microstructure on hydrolytic degradation ...
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MICROSTRUCTURE AND PROPERTIES OF NANO - eCM
18 2009 (pages 63-74). ISSN 1473- ... gelation for 2 hours due to the presence of PLLA and PCL ... ease of processing, adjustable degradation and mechanical ... Recently, intensive studies showed that cells recognized ... pressure liquid chromatography (HPLC) pump, three ..... Effects of gelation temperature (Tgel) on the.
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Curriculum Vitae - Drexel University
Apr 2, 2012 ... 'The Effect of Heat Treatment on Water Sorption in Polylactide and Polylactide ... Physical Journal Special Topics, (2009) 166 103-106. 16. ... 'Moisture Sorption, Transport, and Hydrolytic Degradation in Polylactide,' R.A. ..... Characterization of Coating Microstructure,' R.A. Cairncross*, M. Ivosevic, V. Gupta ...
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based Micro and Nanoparticles for the Controlled Drug Delivery of
tors affecting degradation and drug release rate. ... be further classified into hydrolytically degradable polymers and ... covers synthesis, the effect of particle size and size distribution, ... lactide (PLLA) is a semicrystalline polymer, while poly(dl-lactide) .... and melted or bonded together to form microstructures according to.
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Characteristics of Biodegradable Implants - Scientific Research
Mar 14, 2014 ... effect of rigid plates on bones which leads to the development of stress protection atrophy. ..... Results from kinetic studies revealed that hydrolytic degradation of oli - .... on the fracture property, mechanism and microstructure of PLLA/ .....  Seal, C.K., Vince, K. and Hodgson, M.A. (2009) Biodegradable ...
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Polylactide Conjugates of Camptothecin with Different Drug Release
Nov 25, 2014 ... microstructure, and allow in the case of CMPT-PLA conjugates for the ... water, high toxicity and inactivation through lactone ring hydrolysis at a .... The degradation process is rather slow and regular, ..... of camptothecin—The synthesis, characterization and in vitro studies. .... Polimery 2009, 54, 114–119.
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mechanism of controlled release kinetics from medical - SciELO
(Submitted: July 20, 2009 ; Revised: January 6, 2010 ; Accepted: January 17, 2010). Abstract ... pharmacokinetic-pharmacodynamic effects of drugs ..... polymers undergo hydrolytic and enzymatic ..... degradation of the biodegradable polymer PLA. An .... Studies on in-vitro elution kinetics and in- ... Well validated HPLC.
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Complete PhD Thesis in PDF format.
Oct 23, 2009 ... Tampere 2009 ... been based on the degradation behavior of polymer and the diffusion rate of the drug ... single agent lacking the possibility for enhanced therapeutic effect. ... The release kinetics and some explanatory studies on microstructures, thermal ... In the drug release studies, it was found that the.
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Ahola, Niina; Veiranto, Minna; Rich, Jaana; Efimov Alexander
Hydrolytic Degradation of Composites of Poly(L-lactide-co-ε- ... have an effect on the degradation rate of the polymer matrix. ... Many groups have studied the composites of poly-ε-caprolactone or polylactide and ... Before degradation studies were carried out, the samples were packed and .... Microstructure of the samples.
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Biodegradable Thermoplastic Elastomers - ACS Publications
May 2, 2016 ... Synthesis, Microstructure, and Mechanical Properties. Erin McMullin ... diffraction studies. ... Hydrolytic degradation of this polymer occurs.
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For Peer Review Only - Hal
Jun 6, 2012 ... available PLA and laurate-modified Mg-Al layered double hydroxide ... 2009; Ray and Bousmina 2005; Fomin and Guzeev 2001). .... Only a few studies on this issue have yet been published (Schmidt et .... The migration test procedure used 95% ethanol (HPLC grade ..... Hydrolysis of PLA during migration.
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Polymeric nanomedicines based on poly(lactide) - Cheng Group
Jan 31, 2013 ... mors based on the Enhanced Permeation and Retention effect ... strated that hydrolytic degradation is size dependent for PLA systems, with ...
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33112 - PubAg - US Department of Agriculture
... of neat PLA. The microstructure of the composites indicated that the addition of pMDI ... reported studies were done with short natural fiber reinforced. PLA ... or even detrimental effect on the tensile strength of PLA ... Downloaded by US DEPT OF AGRI MASTER on July 13, 2009 .... PLA hydrolysis and thermal degradation.
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supercritical fluid processing of novel tissue engineering scaffolds
effect of silica on the Tm, Tg and crystallinity of the PLA pre and post SCF ... 1.3.3 Hydrolysis of PLA in neutral media 35 ... 2.5.5 Pore nucleation studies - the effect of silica 73. 184.108.40.206 ... Chapter 3 Scaffold microstructure and connectivity .... Figure 5.6: HPLC trace of scaffolds containing 0% silica after degradation in Ringers.
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Rafael Auras CV - EarthShift Global
Lilly Fellow, August 2008 to April 2009, Michigan State University, MI, USA .... Reactive functionalization of poly(lactic acid), PLA: Effects of the reactive modifier , ..... Holmes, 2015, Effect of Food Simulants in the Hydrolytic Degradation of ..... Studies of Transparent Aluminum Oxide Coated Polylactide Films," 16th IAPRI World.
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Amphiphilic beads as depots for sustained drug release integrated
Apr 29, 2014 ... Dex has a concentration-dependent stimulatory effect ... as PCL and PLLA is described, to our knowledge the release of Dex .... lease kinetics studies, drug- loaded electrospun scaffolds (50 mg in ..... degrade by hydrolysis and complete in vivo degradation occurs over a period of ..... 21 (2009) 3307–3329.
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Enzymatically Degradable Polyester-Based Adhesives - American
Aug 27, 2015 ... The effect of substrate, molar mass, polymer concentration, and ... glycol) (PEG) block copolymers with biodegradable polylactide ... THF (HPLC grade) was used as a solvent (for ... studies were carried out on Fe(acac)3 cross-linked samples. ..... due to the hydrolytic degradation of ester units in the polymer.
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Crosslinked poly(ester anhydrides)for controlled drug delivery
1.2 HYDROLYTIC DEGRADATION AND EROSION .................................................... 11 .... EROSION AND DRUG RELEASE STUDIES . ... Polym. J. 45 (2009) 557-. 564. ... anhydride)s for peptide delivery: effect of oligomer hydrophobicity on PYY3-36 ... PLA polylactide or poly(lactic acid). PLGA poly(lactide-co-glycolide). PLLA.
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curriculum vitae - Qatar University
based on polyethylene, paraffin wax and wood flour” (2009). 18. Supervisor for ... and properties of bionanohybrids based on biocompatible polylactide and carbon ... Supervisor for TE Motaung (Ph.D. in Polymer Science): “Effect of metal oxide nano- particles ...... Morphology and thermal degradation studies of melt- mixed.
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