Effect of creatine supplementation on skeletal muscle of mdx mice
Mar 11, 2004 ... muscles of mdx mice show a dramatic fall in isometric tension when ... cantly increased after creatine supplementation in. DMD patients,8,14 ...
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Creatine supplementation improves intracellular Ca2+ handling and
Creatine supplementation improves intracellular Ca2+ handling and survival in mdx .... Using dystrophic skeletal muscle cells from the mdx mouse model of DMD, we and .... Effects of creatine supplementation on stress-induced 45Ca2+ influx.
[ 1-s2.0-S0014579398013994-main.pdf?_tid=f4b98a60-2119-11e4-9df0-00000aacb361&acdnat=1407735789_9608f298ca93d9607e4976650b316bea - Read/Download File
Effects of creatine supplementation in cystic fibrosis: results of a pilot
and mild to moderate lung disease received daily creatine supplementation during 12 weeks. Patients ..... handling and survival in mdx skeletal muscle. 2q ... skeletal muscle degeneration and enhances mitochondrial function in mdx mice.
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Metabolic profile of dystrophic mdx mouse muscles analyzed with in
mdx mouse, however, does not show significant muscle weakness, and the diaphragm muscle is significantly more ..... In diaphragm samples, age effects were not identified ..... creatine supplementation on skeletal muscle of mdx mice. Muscle.
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The therapeutic potential of oral creatine supplementation in muscle
disturbances in creatine metabolism found in various muscle diseases; and (ii) the potential of oral creatine ... skeletal muscle of both DMD patients and mdx mice, while the levels of K' and ... in Cr metabolism, making a drastic effect of Cr.
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The Effects of Dietary Creatine Supplements on the Contractile
skeletal muscle where it exists as free creatine (Cr) and the high energy .... 86.2. Table 1. The effect of creatine supplementation on the contractile properties of soleus and extensor .... pump activity. In mdx mouse myotubes, increased PCr.
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Articles Creatine monohydrate enhances strength and body - Neotine
May 25, 2004 ... To determine whether creatine monohydrate (CrM) supplementation increases ... enhanced muscle mitochondrial function in mdx mice. ... subgroups of muscular dystrophy, we evaluated the effect of 4 months of CrM ..... showed that green tea extract improved skeletal muscle structure and function in mdx.
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Full-Text PDF - MDPI
Nov 26, 2015 ... body mass, reduction in serum CK levels or changes in creatinine excretion ... [82 ] investigated the effect of Cr supplementation on skeletal muscle ... supplemented mdx mice with Cr in both the food (47 g¨ kg´1) and water (14 ...
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Proteomic assessment of the acute phase of dystrophin deficiency in
The mdx mouse suffers an early necrotic bout in the hind limb muscles lasting from ... Additionally, chronic effects of dystrophin deficiency can be seen in the diaphragm, ... were performed to determine protein expression in dystrophic skeletal muscle. ..... Additionally, supplementation with creatine monohydrate resulted in ...
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Enhanced Dystrophic Progression in mdx Mice by Exercise - Free
degeneration (taurine or creatine 10% in chow) or to stimulate regeneration ... for the life-threat- ening progressive skeletal muscle degeneration in Duchenne .... effect of exercise between the two strains (control and mdx), the data regarding the ...... creatine supplementation to mdx myotubes counteracts the increase in ...
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Incubating Isolated Mouse EDL Muscles with Creatine Improves
Aug 5, 2011 ... transported into skeletal muscle by a Na+-dependent transmem- brane protein  . ... In addition they did not examine the effects of creatine supplementation on ..... hindlimb skeletal muscle of the mdx mouse. J Muscle Res ...
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Review Article Creatine, L-Carnitine, and 3 Polyunsaturated Fatty
Aug 6, 2014 ... To date, the effects of creatine supplementation on muscle growth and muscle .... For instance, in mdx mice (a model of dys- trophinopathy), an ...
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Matrix metalloproteinase-2 ablation in dystrophin-deficient mdx
Feb 14, 2011 ... MMP-2 in dystrophin-deficient muscle by using mdx mice with .... smaller in the skeletal muscle of mdx/MMP-2-/- mice at 3 months of age than .... MMP-2 does not affect the degradation of DGC components in the process of ...... Creatine supplementation attenuates corticosteroid-induced muscle wasting and.
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Matrix metalloproteinase-2 ablation in dystrophin-deficient mdx
Feb 14, 2011 ... Muscle power, evaluated using the hanging wire test and serum creatine ... impaired in the skeletal muscle of mdx/MMP-22/2 mice, we examined .... determine whether other genes affect pathology in mdx/. MMP-22/2 ...... J.A.B. ( 2007) Creatine supplementation attenuates corticosteroid-induced muscle ...
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The different impact of a high fat diet on dystrophic mdx and control
regeneration, and the eventual replacement of skeletal muscle by fatty and fibrous ... mdx mice (yet no change in muscle morphology of control C57BL/10 mice), suggesting a ... supplementation (creatine and glutamine) in DMD patients and ...
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Duchenne muscular dystrophy: Focus on pharmaceutical and
with amino-acids such as creatine, specific anti-inflammatory drugs and perhaps ... and nutritional supplementation as potential therapies to ... Skeletal muscle necrosis in the mdx mouse. ... Corticosteroids have a catabolic effect on muscle.
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Linda K. McLoon - CiteSeerX
Feb 29, 2008 ... mdx mouse model of Duchenne muscular dystrophy. Linda K. McLoon. Departments ... In the DMD patients, their skeletal muscles are subjected to ongoing cycles of ... The antifibrotic effects of halofuginone prevented collagen-in - ..... T, Ruegg UT. Creatine supplementation reduces skeletal muscle degen-.
[ H1505 Focus on Fibrosis.pdf - Read/Download File
Creatine - Longwood Herbal Task Force
effects of creatine supplementation in patients with chronic heart failure10,11. .... In vitro data: Dystrophic skeletal muscle cells from mice and Duchenne muscular ..... intracellular Ca2+ handling and survival in mdx skeletal muscle cells. FEBS.
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Download Book (PDF, 32665 KB) - Springer
Ergogenic Effects of Creatine in Sports and Rehabilitation. 245 ..... improve calcium homeostasis in the mdx muscular dystrophy mouse model (Pulido ..... 2002, Creatine supplementation reduces skeletal muscle degeneration and enhances ...
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Nutrition Strategies to Improve Physical Capabilities in - CiteSeerX
hypothesized to result from either a fragile or weakened skeletal muscle membrane5,6 or altered cell ... theless, despite these side effects, a recent panel of experts recommended glucocor- .... and nutritional interventions as therapeutic agents in mdx mice and DMD. Among ..... Creatine supplementation reduces skel -.
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