Correction of the bleeding time in treated patients with severe von
prolonged bleeding time (BT) in patients with von Willebrand disease (VWD), perusal ... treatment of severe VWD, and that an intact multimeric structure in ...
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Ddavp-induced correction of prolonged bleeding time in patients
Fourteen patients had "isolated prolonged bleeding time", and in 2 of these cases ... This patient has cyclooxygenase deficiency, and a severe hemorrhagic ... by treatment with DDAVP in many patients with mild hemophilia A or von Willebrand's disease. ... Since the von Willebrand factor seems to bind specifically to platelet ...
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Correction of Bleeding Symptoms in von Willebrand Factor
was corrected after injection of WT mvWF cDNA in Vwf / mice whereas noninjected ... Injection of the GpIIbIIIa and the collagen binding mutants in Vwf / mice also resulted in a correction of bleeding time ..... mimics the clinical situation where VWD patients are treated .... A mouse model of severe von Willebrand disease:.
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von Willebrand Disease : A Clinico-haematological - medIND
Oct 7, 2002 ... antifibrinolytics were used as primary modalities of treatment. Conclusion ... Key Words : Bleeding disorders; von Willebrand Disease. Material and .... born of a consanguineous marriage, showed partial correction, the other eight ..... prolonged bleeding times of patients of severe von Willebrand disease ...
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desmopressin (ddavp) in the treatment of bleeding disorders - Wfh.org
Desmopressin in acquired and drug-induced bleeding disorders . ... express or implied, that drug doses or other treatment recommendations in this publication are correct. For these reasons it is ... first time to treat patients with hemophilia A and von .... observation that patients with VWD type 3 treated with .... Type 3 ( severe) ...
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Antihemophilic Factor/von Willebrand Factor Complex (Human
patients with classical hemophilia (hemophilia A) and von Willebrand disease ... This component is considered to be important for correcting the coagulation ..... 0.5 times the full dose at intervals of 6, 8, or 12 hours after surgery as ...... inactivated plasma concentrates for treatment of severe von Willebrand disease: A cross-.
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Proteolysis of von Willebrand Factor in Therapeutic - BluePatent
bleeding time-the laboratory hallmark of the primary he- mostasis defect in von ... trates may not be satisfactory in correcting the prolonged bleeding time. ... tor VI11 and vWF and used for the treatment of patients in the last. IO years, thus ..... from untreated patients with severe hemophilia A or von Willebrand disease was ...
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Platelet von Willebrand Factor in Inherited and Acquired Bleeding
centrated in platelets are von Willebrand factor (vWF) ... must be transfused to correct defective hemostasis .... rarest and most severe form of the disease .... patients have a prolonged bleeding time, .... patients treated with plasma fractions (41,.
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Alphanate® (Antihemophilic Factor/von Willebrand Factor Complex
indicated for patients with severe VWD (Type 3) undergoing major surgery. ... Treatment and Prevention of Bleeding Episodes and Excess Bleeding During ...... correction of the bleeding time (BT), VWF multimer pattern, and treatment efficacy .
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Management of severe chronic thrombocytopenia in von
Keywords: von Willebrand's disease type 2B; chronic ... prolonged bleeding time, thus correcting the underlying ... treatment of choice in patients with vWD types.
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Comparison of Four Virus-Inactivated Plasma - Blood Journal
... has been the treatment of choice in patients with severe von Willebrand disease (vWD) ... prolonged bleeding time (BT), the two laboratory hallmarks of the disease. ... I of treatment are to correct the deficiency of plasma factor VI11 coagulant ...
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open first page preview - ScienceDirect.com
at 4°C.1 The precipitate, rich in factor VIII, von. Willebrand factor ... von Willebrand factor levels in patients with von. Willebrand ... for the correction of bleeding time in patients with severe von Wille- ... be corrected by cryoprecipitate, 3,6,7 but may be corrected ... the favored agent for the treatment of patients with hemophilia A ...
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Download as a PDF - CiteSeerX
Proteolysis of von Willebrand Factor and Shear Stress. Print ISSN: 0009-7322. .... limits in all patients tested before correction of the aortic .... patients with type 3 severe vWD are treated to raise their plasma .... Correction of the bleeding time.
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Uremic bleeding - Kidney International
The platelet count, prothrombin time, and activated partial ... uremic patients results in a shortening of prolonged bleeding times ... cyclic endoperoxides and, therefore, of TXA2; aspirin-treated ... of von Willebrand multimers in the plasma, as in severe type-I ..... lack of immediate correction of the prolonged bleeding time by.
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Porcine and Canine von Willebrand Factor and von Willebrand
Dec 29, 2010 ... Table 1: Differential correction of phenotype of VWD swine by transplantation ...... bleeding time in treated patients with severe von Willebrand.
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Von Willebrand's Disease - Annual Reviews
(II), prepared from Cohn's fraction I, corrected not only the AHF deficiency, but also the ... The VWF not only corrects the prolonged bleeding time in patients with ... Administration of AHF concentrate to a patient with severe VWD has, as pointed ..... and common complication in the treatment with plasma concentrate is serum.
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Treatment of von Willebrand's Disease - Lach
Aug 12, 2004 ... of factor VIII and a prolonged bleeding time (the bleeding time is ..... Patients with type 1 von Willebrand's disease, who have a functionally ...
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Alphanate® (Antihemophilic Factor/von Willebrand Factor - Grifols
Carefully monitor patients treated with AHF products for the development of FVIII .... of bleeding time correction, in subjects with moderate and severe VWD.
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Hemophilia & von Willebrand Disease 2004 Valentino 1. A newborn
including measurements of the PT, aPTT, bleeding times and fibrinogen. The ... Patients with von Willebrand disease are most likely to have which of the .... threatening bleeding in a boy with severe hemophilia complicated by a high- .... presents to the hemophilia treatment center with a new right knee bleed which does.
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Acquired von Willebrand Disease
of prolonged bleeding time and decreased levels of vWF antigen, ristocetin ..... those with severe trauma. .... Treatment of acquired von Willebrand syndrome in patients with ... Willebrand disease: correction of hemostatic defect by high-dose.
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