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Cathepsin D Agglutinators and Neutral Protease Agglutinators in
tion of agglutinators against the cathepsin D site in IgG. (CDA) and a neutral protease site in IgC (NPA) by rheumatoid synovial tissue. Seven of 11 specimens  ...
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Production of agglutinators and rheumatoid factors in plasma cells of
“neutral protease agglutinators” (9) are synthesized by synovial tissues of ... tologous Fab, fragments produced by cathepsin D in- duce synovitis when injected ...
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Experimental arthritis of rabbits caused by intra-articular injection of
(RA). In thejoint, cathepsin D Fab2 appears to act as a fairly strong antigen. Evidence for this is ... intact molecule(Litwin, 1968; Mandy, 1966a, b, knownin man as agglutinators (Osterland and others,. 1967 ... shown that specific proteases unmask specific anti- gens that .... same material was fixed in neutral buffered formalin.
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Pathogenesis of rheumatoid arthritis: A vascular hypothesis
Identification of factors operative early in the pathogenesis of RA, before it ...... Boni A. Cathepsin D agglutinators and neutral protease agglutinators in rheuma-  ...
[ 1-s2.0-0049017282900208-main.pdf?_tid=1743b402-22c2-11e5-be76-00000aacb361&acdnat=1436065451_3ab7051d147233eddb4f7eca996273f8 - Read/Download File

Cathepsin G from human polymorphonuclear leukocytes cleaves
Cathepsin G, the chymotrypsin-like enzyme from human polymorphonuclear .... Gel chromatography of IgM proteolytic fragments. .... the two major neutral serine proteinases from human polymorphonuclear leukocytes has .... Baici A., Salgam P. & Boni A. (1981) Production of agglutinators and rheumatoid factors in plasma  ...
[ 1-s2.0-016158908290373X-main.pdf?_tid=e1d08fbc-3f99-11e5-a775-00000aab0f6c&acdnat=1439236765_37da11aca6cd12d8148053c46829c901 - Read/Download File

Cleavage of IgG by Elastase-Like Protease (ELP) of Human
Neutral proteases (6) of polymorphonuclear granulocytes (PMN), especially the ELP, ... of patients with rheumatoid arthritis (RA) in connection with a high proteolytic activity at .... According to the producer, unspecific agglutinators were eliminated by .... The molecular weights were estimated as 46,000-47,000 d for Fab-ELP, ...
[ 1-s2.0-S0171298582800533-main.pdf?_tid=0eb0747e-bd29-11e3-a98f-00000aacb35e&acdnat=1396747159_bf55f0606d37644771c2bedfd0f8e64d - Read/Download File

Cloning and expression of carp cathepsin Z: Possible involvement in
Jan 26, 2008 ... Carp cathepsin Z has proteolytic activity toward vitellogenin that could be inhibited by inhibitors ... (Cataldo et al., 1991), rheumatoid arthritis (Hashimoto et al., ... gradation, fish cathepsin D could process vitellogenin into yolk ...... In carp, cystatin had been demonstrated to agglutinate .... The major neutral.
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