Cardiac metabolism measured noninvasively by hyperpolarized
Cardiac Metabolism Measured Noninvasively by. Hyperpolarized 13C MRI. Klaes Golman,1 J. Stefan Petersson,1* Peter Magnusson,1 Edvin Johansson,1 Per ...
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Hyperpolarized 13C magnetic resonance reveals early and
a model of heart failure using non-invasive hyperpolarized [13C]pyruvate with MR, the .... Magnetic resonance imaging and spectroscopy (MRI and MRS) ...... Hansson G, Mansson S. Cardiac metabolism measured noninvasively by hyperpo-.
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Cardiovascular Applications of Hyperpolarized MRI - Springer
Jan 19, 2011 ... approach for the assessment of cardiac structure and function. ..... Cardiac metabolism measured noninvasively by hyperpolarized 13C MRI.
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Hyperpolarized [1‐13C]Pyruvate MRI for Noninvasive
maternal heart and each placenta and fetal liver in all slices in the 1H images. These ROIs were ... fetoplacental metabolism and transport of pyruvate in guinea pigs. Hyperpolarized 13C .... hyperpolarized 13C MRI for noninvasive examination of fetoplacental .... vate and lactate signals measured in the placentae by the.
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A new direction for polarized carbon-13 MRI
Apr 7, 2009 ... A new direction for polarized carbon-13 MRI. Rahim R. Rizi1 ... tion of DNP- hyperpolarized 13C liquid- phase agents for .... (2008) Cardiac metabolism measured noninvasively by hyperpolarized 13C MRI. Magn Reson.
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Hyperpolarized 13C Metabolic Imaging Using Dissolution DNP
the physics of magnetic resonance imaging (MRI) detection. ACTIVITY ... Key Words: hyperpolarized 13C; DNP; metabolic imaging; pyruvate. J. Magn. Reson.
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MetabolicImaging - Heart and Metabolism
Keywords: dynamic nuclear polarization; MRI; cardiac metabolism; 13C. □ Heart Metab. ..... metabolism measured noninvasively by hyperpolarized C-13 · MRI.
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MRI/MRS & PET Imaging - Sigma-Aldrich
Metabolic imaging by hyperpolarized 13C magnetic resonance imaging for in ... C.; Hansson, G.; Månsson, S. Cardiac metabolism measured noninvasively by.
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Potential clinical roles for metabolic imaging with hyperpolarized [1
Feb 28, 2016 ... with measurements of [1-13C]pyruvate metabolism in prostate ... 2007;Gallagher et al., 2009) and cardiac tissue (Merritt et al., 2007;Golman et al., ..... Cardiac metabolism measured noninvasively by hyperpolarized 13C MRI.
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Hyperpolarised Media - ismrm
May 9, 2016 ... Using Hyperpolarized MRI to Study Cardiac Metabolism. Damian J. Tyler ... 3D Dynamic Hyperpolarized 13C-Pyruvate MR Metabolic Imaging. Hsin-Yu Chen ... Mis-Estimation & Bias of Hyperpolarized ADC Measurements Due to. Jeremy W. ... Noninvasive Biomarkers for the Diagnosis of Hepatic Ischemia.
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Download as a PDF - CiteSeerX
Oct 8, 2013 ... As a result, changes in cardiac metabolic substrate utilization are ..... Cardiac metabolism measured noninvasively by hyperpolarized 13C. MRI.
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Direct noninvasive estimation of myocardial tricarboxylic acid cycle
Aug 19, 2015 ... but direct noninvasive quantification of metabolic fluxes is challenging ... hyperpolarized [1-13C]acetate can enable the measurement of ... TCA cycle flux; DNP, dynamic nuclear polarization; MRI, magnetic resonance imaging;.
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Production of Hyperpolarized [1, 4-¹³C₂] Malate from [1, 4-¹³C₂
hyperpolarized 13C-labeled malate from [1,4-13C2]fumarate ap pears to ...... ( 2008) Cardiac metabolism measured noninvasively by hyperpolarized. 13C MRI.
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Hyperpolarized Magnetic Resonance as a - ACS Publications
Nov 4, 2014 ... ... magnetic resonance allows for noninvasive measurements of ... MR imaging ( MRI) can be performed at relatively ... signal allows quantitative measurements of the incorporation of ... developed to provide hyperpolarized (HP) 13C metabolic ..... emphasize glucose utilization, i.e., brain metabolism or heart.
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Magnetic Resonance Spectroscopy in Myocardial Disease
Magnetic resonance spectroscopy (MRS) is the only noninvasive, ... noninvasive metabolic imaging;; 31P spectroscopy;; cardiac energetics ...... A broadband phased-array system for direct phosphorus and sodium metabolic MRI on a clinical scanner ... Hyperpolarized 13C allows a direct measure of flux through a single ...
[ 1-s2.0-S1936878X08004099-main.pdf?_tid=e963147e-4c43-11e4-98f6-00000aab0f6c&acdnat=1412481709_2fecea58e9f801726ca9ce684600b414 - Read/Download File
In Vivo hyperpolarized carbon13 magnetic resonance spectroscopy
study, we used hyperpolarized carbon 13 (13C)-labeled pyruvate magnetic resonance ... function in the liver by a noninvasive in vivo method. .... In Vivo Measurements of Hepatic Metabolism ... acquired over 1 minute in a 9.4-T preclinical MRI scan- ..... cardiac substrate supply: a hyperpolarised 13C magnetic resonance.
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Curriculum Vitae - Center for Hyperpolarization in Magnetic
cardiac metabolism studies in pigs, Measurement: Journal of the International .... imaging and hyperpolarized 13C MRI of pyruvate metabolism as noninvasive.
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Teaching Syllabus - ESMRMB
Oct 1, 2015 ... novel methods of assessing myocardial metabolism offer the possibility of detecting metabolic .... Hansson G, Mansson S (2008) Cardiac metabolism measured noninvasively by hyperpolarized 13C MRI. Magn Reson Med 59 ...
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ABSTRACTS of TALKs and POSTERS - European Society for
Feb 2, 2016 ... beating heart with MRI and deciphering cardiac blood flows. .... Measurement of myocardial blood flow and perfusable tissue .... Multimodal imaging of cardiac metabolism in mouse models of ...... Furthermore, the combination of hyperpolarized 13C MRS and co-administration of separate imaging agents ...
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Optimizing flip angles for metabolic rate estimation in hyperpolarized
in hyperpolarized carbon-13 MRI .... els of metabolic flux measured using MR spectroscopy ,. . It is shown ... which has been commonly applied for hyperpolarized 13C ...... and alanine: Noninvasive biomarkers for prostate cancer detection and ... flux in the heart using hyperpolarized carbon-13 magnetic resonance,”.
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